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TPK1 gRNA (BRDN0001148855)

Plasmid

#77429

Purpose

3rd generation lentiviral gRNA plasmid targeting human TPK1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TPK1 (TPK1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TNK2 gRNA (BRDN0001148153)

Plasmid

#75582

Purpose

3rd generation lentiviral gRNA plasmid targeting human TNK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TNK2 (TNK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TNK2 gRNA (BRDN0001148514)

Plasmid

#75583

Purpose

3rd generation lentiviral gRNA plasmid targeting human TNK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TNK2 (TNK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
TNK2 gRNA (BRDN0001149049)

Plasmid

#75584

Purpose

3rd generation lentiviral gRNA plasmid targeting human TNK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TNK2 (TNK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
TNK2 gRNA (BRDN0001149191)

Plasmid

#75585

Purpose

3rd generation lentiviral gRNA plasmid targeting human TNK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TNK2 (TNK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TYRO3 gRNA (BRDN0001147880)

Plasmid

#76227

Purpose

3rd generation lentiviral gRNA plasmid targeting human TYRO3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TYRO3 (TYRO3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TYRO3 gRNA (BRDN0001146050)

Plasmid

#76228

Purpose

3rd generation lentiviral gRNA plasmid targeting human TYRO3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TYRO3 (TYRO3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
TYRO3 gRNA (BRDN0001147403)

Plasmid

#76229

Purpose

3rd generation lentiviral gRNA plasmid targeting human TYRO3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TYRO3 (TYRO3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FSynIGW2

Plasmid

#26671

Depositor

Gerardo Morfini

Type

Empty backbone

Use

Lentiviral

Tags

IRES-EGFP

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 18, 2011

Availability

Academic Institutions and Nonprofits only
pLenti X2 Zeo/pTER shMDC1 (764-1)

Plasmid

#22194

Depositor

Eric Campeau

Insert

shMediator of DNA damage checkpoint 1

Use

Lentiviral and RNAi

Tags

Expression

Mutation

Promoter

Available since

Dec. 18, 2009

Availability

Academic Institutions and Nonprofits only

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miR-144-451 Trap

Plasmid

#61488

Purpose

to knockdown endogenous miR144 and miR451 levels

Depositor

Curt Civin

Article

Kim et al Br J Haematol. 2014 Oct 14. doi: 10.1111

Insert

miR-144-451 Trap

Use

Lentiviral

Tags

GFP

Expression

Mammalian

Mutation

Promoter

bidirectional phosphoglycerate kinase promoter (b…

Available since

Oct. 20, 2015

Availability

Academic Institutions and Nonprofits only
MAPK10 gRNA (BRDN0001148192)

Plasmid

#75981

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK10

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK10 (MAPK10 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PIM2 gRNA (BRDN0001149335)

Plasmid

#76383

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIM2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIM2 (PIM2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

Aug. 16, 2016

Availability

Academic Institutions and Nonprofits only

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PIM2 gRNA (BRDN0001148470)

Plasmid

#76382

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIM2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIM2 (PIM2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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AB.pCCL.sin.cPPT.GFP.miR-16-2-3p.sensor.PGK.dNGFR.WPRE

Plasmid

#85876

Purpose

Sensor Plasmid

Depositor

Brian Brown

Article

Mullokandov et al Nat Methods. 2012 Jul 1;9(8):840-6. doi:

Insert

miR-16-2-3p Sensor (MIR16-2 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

PGK

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only

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FCIV1-GR SS287AA/S155A

Plasmid

#72700

Purpose

Lentiviral expression of GR-2A phosphodeficient mutant (2nd generation)

Depositor

Freddy Jeanneteau

Article

Lambert et al Mol Cell Biol. 2013 Sep;33(18):3700-14.

Insert

GR (Nr3c1 Rat)

Use

Lentiviral

Tags

IRES-Venus

Expression

Mammalian

Mutation

SS287AA/S155A

Promoter

ubiquitin

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
INSRR gRNA (BRDN0001147393)

Plasmid

#78060

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSRR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSRR (INSRR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
INSRR gRNA (BRDN0001149046)

Plasmid

#78061

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSRR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSRR (INSRR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
INSR gRNA (BRDN0001148089)

Plasmid

#75507

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSR (INSR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
INSR gRNA (BRDN0001149243)

Plasmid

#75508

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSR (INSR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge