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pHAGE-EGFR-P596S

Plasmid

#116285

Purpose

Lentiviral expression of EGFR P596S

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Tags

Expression

Mutation

P596S

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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MCM7 E4.2 gRNA

Plasmid

#90765

Purpose

3rd generation lentiviral gRNA plasmid targeting human MCM7

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

MCM7 (Guide Designation E4.2)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 21, 2017

Availability

Academic Institutions and Nonprofits only

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EF1a_MYC deltab_P2A_Hygro_Barcode

Plasmid

#120507

Purpose

Barcoded lentiviral vector to express MYC deltab in mammalian cells under control of EF1a promoter. Barcoded for transcript detection in single cell RNA-seq.

Depositor

Prashant Mali

Article

Parekh et al Cell Syst. 2018 Nov 12. pii: S2405-4712(

Insert

MYC deltab (MYC Human)

Use

Lentiviral

Tags

Expression

Mutation

Deletion of basic motif

Promoter

EF1a

Available since

Feb. 7, 2019

Availability

Academic Institutions and Nonprofits only

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IKBKB gRNA (BRDN0001145579)

Plasmid

#76090

Purpose

3rd generation lentiviral gRNA plasmid targeting human IKBKB

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IKBKB (IKBKB Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TALE10

Plasmid

#35425

Depositor

Feng Zhang

Article

Zhang et al Nat Biotechnol. 2011 Feb;29(2):149-53. d

Insert

TALE10

Use

Lentiviral

Tags

EGFP

Expression

Mammalian

Mutation

Promoter

EF-1a

Available since

March 30, 2012

Availability

Academic Institutions and Nonprofits only

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EPHA3 gRNA (BRDN0001147883)

Plasmid

#76743

Purpose

3rd generation lentiviral gRNA plasmid targeting human EPHA3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

EPHA3 (EPHA3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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EPHA3 gRNA (BRDN0001147140)

Plasmid

#76745

Purpose

3rd generation lentiviral gRNA plasmid targeting human EPHA3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

EPHA3 (EPHA3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MINK1 gRNA (BRDN0001146260)

Plasmid

#76260

Purpose

3rd generation lentiviral gRNA plasmid targeting human MINK1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MINK1 (MINK1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MINK1 gRNA (BRDN0001147795)

Plasmid

#76262

Purpose

3rd generation lentiviral gRNA plasmid targeting human MINK1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MINK1 (MINK1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pCDF1-PTPRD-D1248N

Plasmid

#25646

Depositor

Todd Waldman

Article

Solomon et al Cancer Res. 2008 Dec 15. 68(24):10300-6.

Insert

Protein tyrosine phosphatase receptor-type delta (PTPRD Human)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

tumor-derived mutation created by site-directed m…

Promoter

Available since

Nov. 8, 2010

Availability

Academic Institutions and Nonprofits only
PANK2 gRNA (BRDN0001149459)

Plasmid

#76809

Purpose

3rd generation lentiviral gRNA plasmid targeting human PANK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PANK2 (PANK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MPP1 gRNA (BRDN0001149326)

Plasmid

#77804

Purpose

3rd generation lentiviral gRNA plasmid targeting human MPP1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MPP1 (MPP1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CAMK2A gRNA (BRDN0001149531)

Plasmid

#76928

Purpose

3rd generation lentiviral gRNA plasmid targeting human CAMK2A

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CAMK2A (CAMK2A Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SNRK gRNA (BRDN0001146508)

Plasmid

#76732

Purpose

3rd generation lentiviral gRNA plasmid targeting human SNRK

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SNRK (SNRK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SNRK gRNA (BRDN0001146665)

Plasmid

#76733

Purpose

3rd generation lentiviral gRNA plasmid targeting human SNRK

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SNRK (SNRK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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sgRNA3_NANOG

Plasmid

#64155

Purpose

Photoactivatable transcription system. Lentiviral expression of NANOG sgRNA3. Also contains a CMV-puro-t2A-mCherry expression cassette

Depositor

Moritoshi Sato

Article

Nihongaki et al Chem Biol. 2015 Feb 19;22(2):169-74. doi

Insert

sgRNA3_NANOG (NANOG Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

April 15, 2015

Availability

Academic Institutions and Nonprofits only

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SMG1 gRNA (BRDN0001149508)

Plasmid

#75772

Purpose

3rd generation lentiviral gRNA plasmid targeting human SMG1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SMG1 (SMG1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pFUT

Plasmid

#29643

Depositor

Didier Trono

Article

Laurenti et al Stem Cells. 2010 Aug . 28(8):1390-8.

Insert

tetO

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Sept. 14, 2011

Availability

Academic Institutions and Nonprofits only

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pHAGE-TAOK1__PIPOX

Plasmid

#116839

Purpose

Lentiviral expression of TAOK1__PIPOX fusion

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

TAOK1__PIPOX

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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NUP107 F8.2 gRNA

Plasmid

#90811

Purpose

3rd generation lentiviral gRNA plasmid targeting human NUP107

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

NUP107 (Guide Designation F8.2)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 20, 2017

Availability

Academic Institutions and Nonprofits only

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