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Plasmid#98315PurposeLentiviral expression of API5DepositorInsertAPI5 (API5 Human)
UseLentiviralTagsV5ExpressionMammalianMutationPromoterE1FaAvailable sinceAug. 23, 2017AvailabilityAcademic Institutions and Nonprofits only -
pLenti-X1-Neo-NDUFB4
Plasmid#139840PurposeLentiviral expression of human NDUFB4DepositorInsertNDUFB4 (NDUFB4 Human)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceApril 21, 2020AvailabilityAcademic Institutions and Nonprofits only -
pScalps_puro_mIL-2Rα RK
Plasmid#59920PurposeExpresses mouse interleukin-2 receptor alpha chain mutatedDepositorInsertinterleukin 2 receptor alpha (Il2ra Mouse)
UseLentiviralTagsExpressionMutationchanged sequence of the intracellular (C-terminal…PromoterAvailable sinceOct. 3, 2014AvailabilityAcademic Institutions and Nonprofits only -
pHR-LAT-Y6F YYYY-mCitrine (XSB586)
Plasmid#78515PurposeLentiviral vector for expressing LAT-Y6F YYYY-mCitrine (3 Grb2 binding sites)DepositorInsertLAT (LAT Human)
UseLentiviralTagsmCitrineExpressionMammalianMutationPromoterAvailable sinceAug. 9, 2018AvailabilityAcademic Institutions and Nonprofits only -
pINDUCER20-hSRF-3xHA (#757)
Plasmid#78344PurposeDoxycycline-inducible lentiviral overexpression of human SRF ORF with a 3xHA tagDepositorInsertSRF (SRF Human)
UseLentiviralTags3x HA tagExpressionMutationPromoterTRE2Available sinceJuly 29, 2016AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR - Amplicon, JAK2 sgRNA 2
Plasmid#70660PurposeExpresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic JAK2 amplicon-targeting sgRNA element from U6 promoter. Lentiviral backboneDepositorInsertsgRNA against JAK2 amplicon found in AML-derived HEL cell line (JAK2 )
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterAvailable sinceOct. 29, 2015AvailabilityAcademic Institutions and Nonprofits only -
FYN gRNA (BRDN0001145913)
Plasmid#77245Purpose3rd generation lentiviral gRNA plasmid targeting human FYNDepositorInsertFYN (FYN Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJune 30, 2016AvailabilityAcademic Institutions and Nonprofits only -
pCSIIneo-TRE-hPhyB621- mCherry-HRasCT
Plasmid#139482PurposeExpresses PhyB621-mCherry-HRasCT in mammalian cells.DepositorInsertPhyB621 (PHYB Mustard Weed)
UseLentiviralTagsmCherry-HRasCTExpressionMammalianMutationG229L and deletion of aa Y at position 235 in mch…PromoterTet responsible elementAvailable sinceApril 16, 2020AvailabilityAcademic Institutions and Nonprofits only -
H2AFX B3.3 gRNA
Plasmid#90702Purpose3rd generation lentiviral gRNA plasmid targeting human H2AFXDepositorInsertH2AFX (Guide Designation B3.3)
UseCRISPR and LentiviralTagsExpressionMutationPromoterU6Available sinceJuly 19, 2017AvailabilityAcademic Institutions and Nonprofits only -
H2AFX B4.3 gRNA
Plasmid#90703Purpose3rd generation lentiviral gRNA plasmid targeting human H2AFXDepositorInsertH2AFX (Guide Designation B4.3)
UseCRISPR and LentiviralTagsExpressionMutationPromoterU6Available sinceJuly 19, 2017AvailabilityAcademic Institutions and Nonprofits only -
pLEX-FHH-Raf1RBD
Plasmid#120707PurposeExpresses Flag-HA-6xHIS-Raf1 RBD fusion protein in mammalian cells & for virus productionDepositorInsertRaf1 RBD
UseLentiviralTagsFlag-HA-6xHISExpressionMammalianMutationRaf1 amino acids 1-149PromoterCMVAvailable sinceJan. 29, 2019AvailabilityAcademic Institutions and Nonprofits only -
pLJM1-FH-AGO2-S828A
Plasmid#91982PurposeExpresses FLAG-HA-AGO2 (S828A)DepositorInsertAGO2 (AGO2 Human)
UseLentiviralTagsFLAG-HAExpressionMammalianMutationS828APromoterAvailable sinceAug. 25, 2017AvailabilityAcademic Institutions and Nonprofits only -
pHRIG-PRAS40
Plasmid#53599Purposelentiviral expression of constitutively active PRAS40 and EGFPDepositorInsertPRAS40 (AKT1S1 Human)
UseLentiviralTagsIRES-EGFP and mycExpressionMammalianMutationconstitutively active (myristoylated version)PromoterCMVAvailable sinceSept. 8, 2014AvailabilityAcademic Institutions and Nonprofits only -
PAK4 gRNA (BRDN0001148325)
Plasmid#77576Purpose3rd generation lentiviral gRNA plasmid targeting human PAK4DepositorInsertPAK4 (PAK4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-CDC42BPB__RGS6
Plasmid#116810PurposeLentiviral expression of CDC42BPB__RGS6 fusionDepositorInsertCDC42BPB__RGS6
UseLentiviralTagsExpressionMutationPromoterAvailable sinceMarch 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-CDC42BPB__SYNJ2BP
Plasmid#116811PurposeLentiviral expression of CDC42BPB__SYNJ2BP fusionDepositorInsertCDC42BPB__SYNJ2BP
UseLentiviralTagsExpressionMutationPromoterAvailable sinceMarch 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
MAPK11 gRNA (BRDN0001147606)
Plasmid#77482Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK11DepositorInsertMAPK11 (MAPK11 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK11 gRNA (BRDN0001146070)
Plasmid#77483Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK11DepositorInsertMAPK11 (MAPK11 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
WNK4 gRNA (BRDN0001147338)
Plasmid#75656Purpose3rd generation lentiviral gRNA plasmid targeting human WNK4DepositorInsertWNK4 (WNK4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
NUAK1 gRNA (BRDN0001162598)
Plasmid#75577Purpose3rd generation lentiviral gRNA plasmid targeting human NUAK1DepositorInsertNUAK1 (NUAK1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only