Purpose
Expresses a dominant negative Kash control, that lacks the actual Kash domain for LINC complex integration, in addition to fluorescently tagged (mRuby2) α-Actinin-2 on an adenoviral backbone
Inserts
C-terminal end of Nesprin-3 w/o Kash (
Syne3 Mouse)
Actinin alpha 2 (
Actn2 Mouse)
Use
Adenoviral
Tags
Signal Peptide (TOR1A, NM_000113.2), mNeptune2.5,…
Expression
Mammalian
Mutation
deleted Kash domain (GGCGAGGAGGAGCGCAGCTGCGCCCTGG…
Available since
June 28, 2022
Availability
Academic Institutions and Nonprofits only