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Plasmid#71391PurposeHomologues recombination donor plasmid for inserting a FLAG-SNAP-tag at the N-terminus of the TERT locus in human cells. Includes GFP marker flanked by LoxP sites for selection.DepositorInsertTERT (TERT Human)
UseHr donorTagsFLAG-SNAPExpressionMutationPromoterEndogenous TERT promotorAvailable sinceDec. 10, 2015AvailabilityAcademic Institutions and Nonprofits only -
HR-TERT-SV40-GFP
Plasmid#71397PurposeHomologues recombination donor plasmid fo the TERT promotor region introducing a SV-40 driven GFP marker in the TERT promotor. Includes 1kb of TERT coding region in right homologues arm.DepositorInsertTERT (TERT Human)
UseTagsSV-40 GFP insertion in TERT promotorExpressionMutationPromoterEndogenous TERT promotorAvailable sinceDec. 10, 2015AvailabilityAcademic Institutions and Nonprofits only -
pORANGE GFP-Clta KI
Plasmid#131483PurposeEndogenous tagging of Clathrin light chain α: N-terminal (amino acid position: M1)DepositorInsertgRNA and GFP donor (Clta Rat)
UseTagsExpressionMammalianMutationPromoterU6 and CbhAvailable sinceSept. 25, 2019AvailabilityAcademic Institutions and Nonprofits only -
pEF1a-hMLH1dn (og codon)
Plasmid#174823PurposeMammalian expression of human MLH1dn (original codon usage)DepositorInserthuman MLH1dn (original codon usage) (MLH1 Human)
UseTagsExpressionMammalianMutationdeletion of residues 754-756PromoterEF1aAvailable sinceDec. 14, 2021AvailabilityAcademic Institutions and Nonprofits only -
MSCVpic2neo-hTERT-p16 shRNA
Plasmid#164920PurposeExpresses hTERT cDNA and p16 shRNA in mammalian cellsDepositorUseRetroviralTagsHA tagExpressionMutationPromoterAvailable sinceMay 26, 2021AvailabilityAcademic Institutions and Nonprofits only -
FLAG-LoxP-PURO-LoxP-SNAP-TERT
Plasmid#71390PurposeHomologues recombination donor plasmid for inserting a FLAG-SNAP-tag at the N-terminus of the TERT locus in human cells. Includes PURO resistance flanked by LoxP sites for selection.DepositorInsertTERT (TERT Human)
UseHr donorTagsFLAG-SNAPExpressionMutationPromoterEndogenous TERT promotorAvailable sinceDec. 10, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCMV-MMLV-gag-hMLH1dn
Plasmid#195513PurposeMMLV-Gag fused to hMLH1dn with TSTLLMENSS cleavage site between Gag-NES and hMLH1dn. For production of virus like particles with base-editor RNP cargo.DepositorInserthMLH1dn (MLH1 Human)
UseVirus like particleTagsFLAG, NES, and Protease cleavate siteExpressionMammalianMutationHuman MLH1 del754-756PromoterCMVAvailable sinceMay 2, 2023AvailabilityAcademic Institutions and Nonprofits only -
CL20_mEGFP_TRIO_TERT
Plasmid#205946PurposeExpress mEGFP-tagged fusion protein, TRIO_TERT from patient-derived sequenceDepositorUseTagsmEGFPExpressionMammalianMutationPromoterAvailable sinceNov. 9, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR221_SLC10A1
Plasmid#131907PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectorsDepositorInsertSLC10A1 (SLC10A1 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 11, 2019AvailabilityIndustry, Academic Institutions, and Nonprofits -
AcGFP-MLH1
Plasmid#215120PurposeExpresses AcGFP-MLH1 in mammalian cells from a retroviral vector.DepositorInsertMLH1 (MLH1 Human)
UseRetroviralTagsAcGFPExpressionMammalianMutationPromoterCMVAvailable sinceApril 10, 2024AvailabilityAcademic Institutions and Nonprofits only -
TERT - WT
Plasmid#213827PurposeExpresses human telomerase reverse transcriptase, the catalytic subunit of telomeraseDepositorInserthuman TERT (TERT Human)
UseLentiviralTagsExpressionMammalianMutationPromoterTet-responsive promoter PTight, consisting of sev…Available sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pDONR221-SLC10A1_STOP
Plasmid#161073PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.DepositorInsertSLC10A1 (SLC10A1 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceJune 21, 2021AvailabilityIndustry, Academic Institutions, and Nonprofits -
TERT - R865C
Plasmid#213926PurposeExpresses Mutant TERT R865CDepositorInsertMutant TERT R865C (TERT Human)
UseLentiviralTags6x His TagExpressionMammalianMutationArginine 865 changed to CysteinePromoterTet-responsive promoter PTight, consisting of sev…Available sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_WT
Plasmid#81766PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationWTPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.E250K
Plasmid#81614PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationE250KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.T347N
Plasmid#81394PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationT347NPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.F182I
Plasmid#81383PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationF182IPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.E290K
Plasmid#81387PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationE290KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.E110K
Plasmid#81390PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationE110KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB4_p.A137E
Plasmid#81355PurposeGateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB4 (SERPINB4 Human)
UseGateway entry vectorTagsExpressionMutationA137EPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only