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Showing: 4781 - 4800 of 30516 results

  1. pENTR223-CMV-Cre-U6-sgNotch1#1-U6-sgRb1-U6-sgTrp53-U6-sgRbl2

    Plasmid
    #209068
    Purpose
    Entry vector that encodes sgRNAs against mouse Notch1, Rb1, Trp53, Rbl2, and CMV Cre recombinase.
    Depositor
    Matthew Oser
    Article
    Hong et al Cancer Res. 2022 Jan 15;82(2):248-263. d
    Insert
    sgRNAs targeting Notch1, Rb1, Trp53, Rbl2 and Cre recombinase
    Use
    Gateway vector to be used for lr reaction
    Tags
    Expression
    Mutation
    Promoter
    U6
    Available since
    Oct. 26, 2023
    Availability
    Academic Institutions and Nonprofits only
    209068-plasmid-map-sequence-id-412279

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  2. pOTTC1755 - pcDNA3.1 CMV-IE hChR2(H134R)-V5-ER-LBD (ChRERa)

    Plasmid
    #201819
    Purpose
    A plasmid expressing channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a CMV promoter
    Depositor
    Christopher Richie
    Article
    Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd
    Insert
    hChR2(H134R)-V5-ER-LBD (ChRERa)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    pOTTC1751
    Available since
    Oct. 16, 2023
    Availability
    Academic Institutions and Nonprofits only
    201819-plasmid-map-sequence-id-399602

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  3. pCMV-T7-ABE8.20m-SpCas9-NRCH-P2A-EGFP (RMD55)

    Plasmid
    #197501
    Purpose
    CMV and T7 promoter expression plasmid for human codon optimized ABE(8.20) A-to-G base editor with nSpCas9-NRCH(D10A) and P2A-EGFP
    Depositor
    Benjamin Kleinstiver
    Article
    Alves et al Nat Biomed Eng. 2023 Dec 6. doi: 10.1038
    Insert
    pCMV-T7-BPNLS-ABE8.20m-nSpCas9-NRCH-BPNLS-3xFLAG-P2A-EGFP
    Use
    CRISPR; In vitro transcription; t7 promoter
    Tags
    BPNLS and BPNLS-3xFLAG-P2A-EGFP
    Expression
    Mammalian
    Mutation
    ABE8.20 mutations in TadA and nSpCas9-NRCH(D10A/I…
    Promoter
    CMV and T7
    Available since
    March 6, 2023
    Availability
    Academic Institutions and Nonprofits only
    197501-plasmid-map-sequence-id-386690

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  6. pOTTC1584 - pscAAV CMV-IE secreted EGFP-THPKTEL WPRE

    Plasmid
    #188539
    Purpose
    An AAV packaging vector that expresses secreted C-CDNF under control of the EGFP promoter.
    Depositor
    Brandon Harvey
    Insert
    secreted EGFP
    Use
    AAV
    Tags
    CDNF(1-28) and THPKTEL WPRE
    Expression
    Mutation
    Promoter
    CMV-IE
    Available since
    Aug. 22, 2022
    Availability
    Academic Institutions and Nonprofits only
    188539-plasmid-map-sequence-id-370039

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  9. psiCheck2-SV40p-mtIF3(SR)-3xFLAG-CMVp-mito-mTFP1

    Plasmid
    #182380
    Purpose
    Dual expression construct encoding shRNA-resistant mtIF3 and mito-mTFP1 from separate promoters
    Depositor
    Chunghun Lim
    Article
    Lee et al BMC Biol. 2022 Jan 7;20(1):12. doi: 10.1
    Inserts
    mtIF3 (Mtif3 Mouse)
    mito-mTFP1
    Use
    Tags
    3xFlag
    Expression
    Mammalian
    Mutation
    Changed CDS sequence from 'ccacgttcaagtcacga…
    Promoter
    CMV promoter and SV40 promoter
    Available since
    March 30, 2022
    Availability
    Academic Institutions and Nonprofits only
    182380-plasmid-map-sequence-id-358102

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  14. pLV-CMV-EGFP-PolB(K72A)-PAMmut-Hygro

    Plasmid
    #176087
    Purpose
    EGFP fused to the N-terminus of POLB containing the mutation Lys72Ala, a mutation in the PAM site used by POLBKOg1 & a hygromycin resistance cassette
    Depositor
    Robert Sobol
    Article
    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:
    Insert
    PolB (POLB Human)
    Use
    Lentiviral
    Tags
    EGFP
    Expression
    Mammalian
    Mutation
    Mutation in Lys72 to Ala, and mutation in the PAM…
    Promoter
    CMV
    Available since
    Jan. 25, 2022
    Availability
    Academic Institutions and Nonprofits only
    176087-plasmid-map-sequence-id-352865

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  16. pCMV-T7-AcrIIA1(T114A/F115A)-NLS(SV40) (KAC688)

    Plasmid
    #133798
    Purpose
    CMV and T7 promoter expression plasmid for human codon optimized AcrIIA1(T114A/F115A) with C-terminal NLS (SV40)
    Depositor
    Benjamin Kleinstiver, Joseph Bondy-Denomy
    Article
    Osuna et al Cell Host Microbe. 2020 Apr 18. pii: S19
    Insert
    human codon optimized AcrIIA1(T114A/F115A)
    Use
    Tags
    NLS(SV40)
    Expression
    Mammalian
    Mutation
    T114A/F115A
    Promoter
    CMV and T7
    Available since
    April 27, 2020
    Availability
    Academic Institutions and Nonprofits only
    133798-plasmid-map-sequence-id-268051

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Showing: 4781 - 4800 of 30516 results