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Showing: 6561 - 6600 of 7539 results
  1. pcDNA-dCas9-p300 Core (1396/1397 SY/WW)

    Plasmid
    #61363
    Purpose
    encodes S. pyogenes dCas9 with c-terminal fusion of human p300 HAT core (aa 1048-1664; inactivating mutation 1396/1397 SY/WW) driven by CMV promoter
    Depositor
    Insert
    S.pyogenes dCas9 with c-terminal human p300 Core effector fusion (aa 1048-1664 of human p300) (EP300 Synthetic, S. pyogenes, Human)
    Use
    CRISPR and Synthetic Biology
    Tags
    Flag, HA, and SV40 NLS
    Expression
    Mammalian
    Mutation
    D10A; H840A in S.pyogenes Cas9; 1396/1397 SY/WW m…
    Promoter
    CMV
    Available since
    April 10, 2015
    Availability
    Academic Institutions and Nonprofits only
  2. pGL3E-hGPR56 e1m promoter perisylvian polymicrogyria

    Plasmid
    #52299
    Purpose
    Reporter for mutated human GPR56 exon 1m promoter activity. It contains a 15-bp deletion in a conserved noncoding element. The mutated human GPR56 e1m promoter was inserted into pGL3E.
    Insert
    ADGRG1 adhesion G protein-coupled receptor G1 (ADGRG1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mutation
    15-bp deletion in the promoter
    Promoter
    Human GPR56 e1m promoter
    Available since
    April 15, 2014
    Availability
    Academic Institutions and Nonprofits only
  3. pVRC8400-SARS-CoV-2-RBD-XBB-AVI

    Plasmid
    #196619
    Purpose
    Expresses SARS-CoV-2 RBD protein from the XBB variant with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-XBB
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    G339H, R346T, L368I, S371F, S373P, S375F, T376A, …
    Promoter
    Available since
    March 14, 2023
    Availability
    Academic Institutions and Nonprofits only
  4. pVRC8400-SARS-CoV-2-RBD-BQ.1.1-AVI

    Plasmid
    #196618
    Purpose
    Expresses SARS-CoV-2 RBD protein from the BQ.1.1 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-BQ.1.1
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    G339D, R346T, S371F, S373P, S375F, T376A, D405N, …
    Promoter
    Available since
    Feb. 21, 2023
    Availability
    Academic Institutions and Nonprofits only
  5. pVRC8400-SARS-CoV-2-RBD-BJ.1-AVI

    Plasmid
    #196617
    Purpose
    Expresses SARS-CoV-2 RBD protein from the BJ.1 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-BJ.1
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    G339H, R346T, L368I, S371F, S373P, S375F, T376A, …
    Promoter
    Available since
    Feb. 21, 2023
    Availability
    Academic Institutions and Nonprofits only
  6. pVRC8400-SARS-CoV-2-S2P-B.1.621-AVI

    Plasmid
    #181694
    Purpose
    Expresses SARS-CoV-2 S2P protein from the B.1.621 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-S2P-B.1.621 (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    T95I, insert144T, Y144S, Y145N, R346K, E484K, N50…
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  7. pVRC8400-SARS-CoV-2-S2P-C.37-AVI

    Plasmid
    #181693
    Purpose
    Expresses SARS-CoV-2 S2P protein from the C.37 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-S2P-C.37 (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    G75V, T76I, R246N, ∆S247-∆D253, L452Q, F490S, D61…
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  8. pVRC8400-SARS-CoV-2-RBD-SD1-K417N-L452R-T478K-AVI

    Plasmid
    #176457
    Purpose
    Expresses SARS-CoV-2 RBD-SD1 domain containing K417N-L452R-T478K mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-SD1-K417N-L452R-T478K (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    K417N, L452R, T478K
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  9. pVRC8400-SARS-CoV-2-RBD-SD1-N501Y-A570D-AVI

    Plasmid
    #176449
    Purpose
    Expresses SARS-CoV-2 RBD-SD1 domain containing N501Y-A570D mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-SD1-N501Y-A570D (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    N501Y, A570D
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  10. pVRC8400-SARS-CoV-2-RBD-SD1-K417N-E484K-N501Y-AVI

    Plasmid
    #176450
    Purpose
    Expresses SARS-CoV-2 RBD-SD1 domain containing K417N-E484K-N501Y mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-SD1-K417N-E484K-N501Y (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    K417N, E484K, N501Y
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  11. pVRC8400-SARS-CoV-2-RBD-SD1-K417T-E484K-N501Y-AVI

    Plasmid
    #176451
    Purpose
    Expresses SARS-CoV-2 RBD-SD1 domain containing K417T-E484K-N501Y mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-SD1-K417T-E484K-N501Y (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    K417T, E484K, N501Y
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  12. pVRC8400-SARS-CoV-2-RBD-SD1-L452R-E484Q-AVI

    Plasmid
    #176455
    Purpose
    Expresses SARS-CoV-2 RBD-SD1 domain containing L452R-E484Q mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-SD1-L452R-E484Q (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    L452R, E484Q
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  13. pVRC8400-SARS-CoV-2-RBD-K417T-E484K-N501Y-AVI

    Plasmid
    #176441
    Purpose
    Expresses SARS-CoV-2 RBD domain containing K417T-E484K-N501Y mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-K417T-E484K-N501Y (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    K417T, E484K, N501Y
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
  14. pVRC8400-SARS-CoV-2-RBD-K417N-L452R-T478K-AVI

    Plasmid
    #176447
    Purpose
    Expresses SARS-CoV-2 RBD domain containing K417N-L452R-T478K mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag
    Depositor
    Insert
    SARS-CoV-2-RBD-K417N-L452R-T478K (S )
    Use
    Tags
    AVI, HRV3C, and scFc
    Expression
    Mammalian
    Mutation
    K417N, L452R, T478K
    Promoter
    Available since
    March 2, 2022
    Availability
    Academic Institutions and Nonprofits only
Showing: 6561 - 6600 of 7539 results