Addgene

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pD649-HAsp-LAG3-COMP5AP-AviTag-9xHis

Plasmid

#157414

Purpose

Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

Depositor

Chris Garcia

Article

Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

Insert

LAG3 (LAG3 Human)

Use

Tags

COMP5AP-AviTag-9xHis

Expression

Mammalian

Mutation

Promoter

CMV/SP6

Available since

March 8, 2023

Availability

Academic Institutions and Nonprofits only

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MSCV-Neo-GFP/Foxa1

Plasmid

#105506

Purpose

MSCV-driven retroviral Foxa1 expression

Depositor

Christopher Vakoc

Article

Roe et al Cell. 2017 Aug 24;170(5):875-888.e20. do

Insert

Foxa1 (Foxa1 Mouse)

Use

Retroviral

Tags

Expression

Mutation

Promoter

Available since

Feb. 8, 2018

Availability

Academic Institutions and Nonprofits only

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pSIN-hSNCA-NE

Plasmid

#102366

Purpose

Lentiviral overexpression of synuclein alpha

Depositor

Shu Leong Ho

Article

Ho et al Autophagy. 2019 Apr 14:1-24. doi: 10.108

Insert

synuclein alpha (SNCA Human)

Use

Lentiviral

Tags

NE

Expression

Mammalian

Mutation

A silent mutation (333bp downstream of ATG) was i…

Promoter

EF-1a

Available since

April 19, 2018

Availability

Academic Institutions and Nonprofits only

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pDONR223_HTR4_WT

Plasmid

#81915

Purpose

Gateway Donor vector containing HTR4 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, David Root, William Hahn

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

HTR4 (HTR4 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

WT

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHAGE-AXL-C311F

Plasmid

#116116

Purpose

Lentiviral expression of AXL C311F

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

AXL (AXL Human)

Use

Lentiviral

Tags

Expression

Mutation

C311F

Promoter

Available since

April 4, 2019

Availability

Academic Institutions and Nonprofits only

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pDONR223_ADORA2A_WT

Plasmid

#81888

Purpose

Gateway Donor vector containing ADORA2A , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, David Root, William Hahn

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ADORA2A (ADORA2A Human)

Use

Gateway entry vector

Tags

Expression

Mutation

WT

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHAGE-AXL-G736W

Plasmid

#116118

Purpose

Lentiviral expression of AXL G736W

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

AXL (AXL Human)

Use

Lentiviral

Tags

Expression

Mutation

G736W

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-AXL-L423Q

Plasmid

#116119

Purpose

Lentiviral expression of AXL L423Q

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

AXL (AXL Human)

Use

Lentiviral

Tags

Expression

Mutation

L423Q

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-AXL-Q83R

Plasmid

#116120

Purpose

Lentiviral expression of AXL Q83R

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

AXL (AXL Human)

Use

Lentiviral

Tags

Expression

Mutation

Q83R

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-AXL-R506H

Plasmid

#116121

Purpose

Lentiviral expression of AXL R506H

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

AXL (AXL Human)

Use

Lentiviral

Tags

Expression

Mutation

R506H

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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MSCV-Neo-GFP/V5-Foxa1

Plasmid

#105507

Purpose

MSCV-driven retroviral Foxa1 expression (V5-tagged)

Depositor

Christopher Vakoc

Article

Roe et al Cell. 2017 Aug 24;170(5):875-888.e20. do

Insert

Foxa1 (Foxa1 Mouse)

Use

Retroviral

Tags

V5

Expression

Mutation

Promoter

Available since

Feb. 9, 2018

Availability

Academic Institutions and Nonprofits only
pDONR223_ADORA2A_p.R220W

Plasmid

#81425

Purpose

Gateway Donor vector containing ADORA2A , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, David Root, William Hahn

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ADORA2A (ADORA2A Human)

Use

Gateway entry vector

Tags

Expression

Mutation

R220W

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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Anti-Bral1 scFv [N364/42 scFv]

Plasmid

#219494

Purpose

Mammalian Expression Plasmid of anti-Bral1 (Mouse) scFv. Derived from hybridoma N364/42.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Anti-Bral1 (Mus musculus) recombinant mouse scFv. (Hapln2 Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

July 16, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2R)-NE

Plasmid

#215487

Purpose

Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

NE tag

Expression

Mammalian

Mutation

D (second aa) mutated to R

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2E)-NE

Plasmid

#215488

Purpose

Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

NE tag

Expression

Mammalian

Mutation

D (second aa) mutated to E

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2R)-GFP

Plasmid

#215490

Purpose

Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

EGFP

Expression

Mammalian

Mutation

D (second aa) mutated to R

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
FUW-hSNCA(D2E)-GFP

Plasmid

#215491

Purpose

Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

EGFP

Expression

Mammalian

Mutation

D (second aa) mutated to E

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(ARID1A(42))-PGKpuro2ABFP-W

Plasmid

#200467

Purpose

Lentiviral vector expressing gRNA targeting human ARID1A

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

ARID1A(42) (ARID1A Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(ARID1A(44))-PGKpuro2ABFP-W

Plasmid

#200468

Purpose

Lentiviral vector expressing gRNA targeting human ARID1A

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

ARID1A(44) (ARID1A Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 5, 2024

Availability

Academic Institutions and Nonprofits only

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CL20_mEGFP_RABGAP1L_BCAS3

Plasmid

#205906

Purpose

Express mEGFP-tagged fusion protein, RABGAP1L_BCAS3 from patient-derived sequence

Depositor

Richard Kriwacki

Article

Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

Insert

RABGAP1L_BCAS3 (RABGAP1L, BCAS3 Human)

Use

Tags

mEGFP

Expression

Mammalian

Mutation

Promoter

Available since

Nov. 9, 2023

Availability

Academic Institutions and Nonprofits only

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