Purpose
Expresses endonuclease dead (EN- ORF2p E43S, D145N) full length human LINE-1 in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2
Insert
Human LINE-1 (ORFeus-Hs codon optimized sequence, EN- E43S D145N) with ORF2-3xFlag
Expression
Mammalian
Mutation
E43S D145N double mutant EN- endonuclease catalyt…
Available since
May 6, 2024
Availability
Academic Institutions and Nonprofits only