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Showing: 2551 - 2600 of 23249 results
  1. pPV-C1-crRNA(DMD#20_DMD#23)-EF1a-BA

    Plasmid
    #204620
    Purpose
    Expression vector of crRNA (DMD#20) targeting the dystrophin intron 44 just upstream of exon 45, and crRNA(DMD#23)targeting the dystrophin intron 55 just downstream of exon 55. Blasticidin selectable.
    Depositor
    Insert
    crRNA#20 (targeting DMD intron44) and crRNA#23 (targeting DMD intron 55)
    Use
    CRISPR
    Tags
    Expression
    Mutation
    Promoter
    U6
    Available since
    Sept. 27, 2023
    Availability
    Academic Institutions and Nonprofits only
  2. pTR-UF11 (AAV.A11.T)

    Viral Prep
    #157970-AAV.A11.T
    Purpose
    Ready-to-use AAV44.9 in PBS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  3. pTR-UF11 (AAV.A01.T)

    Viral Prep
    #157970-AAV.A01.T
    Purpose
    Ready-to-use AAV2 in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  4. pTR-UF11 (AAV.A09.T)

    Viral Prep
    #157970-AAV.A09.T
    Purpose
    Ready-to-use AAV6 in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  5. pTR-UF11 (AAV.A12.T)

    Viral Prep
    #157970-AAV.A12.T
    Purpose
    Ready-to-use AAV44.9(E531D) in PBS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  6. pTR-UF11 (AAV.A07.T)

    Viral Prep
    #157970-AAV.A07.T
    Purpose
    Ready-to-use AAV2 (trpYF) in BSS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  7. pTR-UF11 (AAV.A10.T)

    Viral Prep
    #157970-AAV.A10.T
    Purpose
    Ready-to-use AAV6(dbY-F+T-V) in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  8. pTR-UF11 (AAV.A06.T)

    Viral Prep
    #157970-AAV.A06.T
    Purpose
    Ready-to-use AAV2 (trpYF) in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  9. pTR-UF11 (AAV.A04.T)

    Viral Prep
    #157970-AAV.A04.T
    Purpose
    Ready-to-use AAV2 (Y444F) in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  10. pTR-UF11 (AAV.A05.T)

    Viral Prep
    #157970-AAV.A05.T
    Purpose
    Ready-to-use AAV2 (Y444F) in BSS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  11. pTR-UF11 (AAV.A08.T)

    Viral Prep
    #157970-AAV.A08.T
    Purpose
    Ready-to-use AAV2(4pMut)dHS in BSS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  12. pTR-UF11 (AAV.A03.T)

    Viral Prep
    #157970-AAV.A03.T
    Purpose
    Ready-to-use AAV2 in BSS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  13. pTR-UF11 (AAV.A02.T)

    Viral Prep
    #157970-AAV.A02.T
    Purpose
    Ready-to-use AAV2 in PBS particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter
    Depositor
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Tags
    GFP
    Available since
    Dec. 21, 2020
    Availability
    Academic Institutions and Nonprofits only
  14. TDP-REGv2 Cryptic PE-Max

    Plasmid
    #216163
    Purpose
    Expression of prime editor PEMax (Plasmid #174820) only in cells with TDP-43 loss of function. Note: It is not recommended to produce lentivirus containing TDP-REG sequences – see Depositor Comments
    Depositor
    Insert
    PEMax for prime editing with internal cryptic exon
    Use
    CRISPR
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 1, 2024
    Availability
    Academic Institutions and Nonprofits only
  15. TDP-REGv2(Gaussia Luciferase)#5 in pTwist-CMV

    Plasmid
    #216164
    Purpose
    Expression of secreted Gaussia Luciferase specifically in cells with TDP-43 loss of function. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments
    Depositor
    Insert
    Gaussia princeps luciferase (with double mutation to improve stability)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 1, 2024
    Availability
    Academic Institutions and Nonprofits only
  16. TDP-REGv1(mCherry-FLAG) in pTwist-CMV

    Plasmid
    #216165
    Purpose
    Expression of mCherry specifically in cells with TDP-43 knockdown. Uses AARS1-derived cryptic exon to control mCherry expression. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments
    Depositor
    Insert
    mCherry with C-terminal FLAG tag
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 1, 2024
    Availability
    Academic Institutions and Nonprofits only
  17. pCSIIpuro-AREG-ScNeo

    Plasmid
    #209897
    Purpose
    To monitor the status of Amphiregulin, the plasmid encodes a recombinant AREG fused extracellularly to the mScarlet fluorescent protein and intracellularly to the mNeonGreen fluorescent protein
    Depositor
    Insert
    AREG-ScNeo (AREG Human)
    Use
    Lentiviral
    Tags
    mNeonGreen and mScarlet
    Expression
    Mutation
    Promoter
    Available since
    Nov. 18, 2024
    Availability
    Academic Institutions and Nonprofits only
  18. pelB-MBP-BB0238-ss

    Plasmid
    #137046
    Purpose
    E. coli expression clone (T7lac promoter) for mature BB0238 (aa 21-256) from B. burgdorferi with N-terminal PelB signal peptide + His10 + mature maltose binding protein + TEV protease cleavage
    Depositor
    Insert
    AAC66635.2 (BB_0238 Borrelia burgdorferi B31)
    Use
    Tags
    PelB signal peptide + His10 + maltose binding pro…
    Expression
    Bacterial
    Mutation
    mature BB0238: lacks the BB0238 signal peptide
    Promoter
    T7lac
    Available since
    April 22, 2020
    Availability
    Academic Institutions and Nonprofits only
  19. pelB-MBP-P66-ss

    Plasmid
    #137045
    Purpose
    E. coli expression clone (T7lac promoter) for mature P66 (aa 22-618) from B. burgdorferi with N-terminal PelB signal peptide + His10 + mature maltose binding protein + TEV protease cleavage
    Depositor
    Insert
    AAC66949.1 (p66 Borrelia burgdorferi B31)
    Use
    Tags
    PelB signal peptide + His10 + maltose binding pro…
    Expression
    Bacterial
    Mutation
    mature P66: lacks the P66 signal peptide
    Promoter
    T7lac
    Available since
    April 17, 2020
    Availability
    Academic Institutions and Nonprofits only
  20. pTR-UF11

    Plasmid
    #157970
    Purpose
    AAV vector plasmid containing the Chimeric CMV/Chicken Beta Actin promoter driving 'humanized' GFP
    Depositor
    Has Service
    AAV.A01.T, AAV.A02.T, AAV.A03.T, AAV.A04.T, AAV.A05.T, AAV.A06.T, AAV.A07.T, AAV.A08.T, AAV.A09.T, AAV.A10.T, AAV.A11.T, and AAV.A12.T
    Insert
    'humanized' e.g. codon optimized GFP
    Use
    AAV
    Tags
    Expression
    Mutation
    Promoter
    chimeric CMV/Chicken Beta actin (CBA)
    Available since
    Oct. 27, 2020
    Availability
    Academic Institutions and Nonprofits only
  21. pelB-MBP-P13-ss

    Plasmid
    #137065
    Purpose
    E. coli expression clone (T7lac promoter) for mature P13 (aa 22-179) from B. burgdorferi with N-terminal PelB signal peptide + His10 + mature maltose binding protein + TEV protease cleavage
    Depositor
    Insert
    AAC66426.1 (BB_0034 Borrelia burgdorferi B31)
    Use
    Tags
    PelB signal peptide + His10 + maltose binding pro…
    Expression
    Bacterial
    Mutation
    mature P13: lacks the P13 signal peptide
    Promoter
    T7lac
    Available since
    April 17, 2020
    Availability
    Academic Institutions and Nonprofits only
Showing: 2551 - 2600 of 23249 results