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Plasmid#87878PurposeE. coli expression of MKK3 aa 1-347DepositorInsertMKK3 (MAP2K3 Human)
UseTags3C protease site and 6xHisExpressionBacterialMutationaa 1-347PromoterT7Available sinceMarch 31, 2017AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-flex-iGluSnFR4s-PDGFR-WPRE
Plasmid#234447PurposeAAV-mediated expression of glutamate sensor with improved sensitivity and slow deactivation kinetics (4s = slow); NGR vector matches or outperforms PDGFR in all conditions tested.DepositorInsertiGluSnFR4s-PDGFR
UseAAV and Cre/LoxTagsIgK chain and Myc epi tag-PDGFR TM DomainExpressionMammalianMutationPromoterCAGAvailable sinceMarch 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP1795 - pAAV-AiE0170h-minBG-iCre(R297T)-BGHpA
Plasmid#220717PurposeAiE0170h is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMarch 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pFastBac-Dual_FluA/H7N9
Plasmid#229860PurposepFastBac Dual vector for co-expression of FluPolA/H7N9 polymerase heterotrimer (PA/PB1/PB2)DepositorInsertsPA_H7N9-FluA
PB1_H7N9-FluA
PB2_H7N9-FluA
UseTags2x-Streptag and 8xHis-tagExpressionInsectMutationPromoterAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pKLBac-FluB-trimer
Plasmid#229859PurposeInfluenza B/Memphis/13/03 polymerase heterotrimer (self-cleaving polyprotein)DepositorInsertsPA, Influenza B (B/Memphis/13/03)
PB1, Influenza B (B/Memphis/13/03)
PB2, Influenza B (B/Los Angeles/1/02)
UseTags2x-Streptag and 8xHis-tagExpressionInsectMutationPromoterAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP13786 - pAAV-AiE0140h-minBG-iCre(R297T)-BGHpA (Alias: CN3786)
Plasmid#230382PurposeAiE0140h is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminRhoAvailable sinceFeb. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP13901 - pAAV-AiE0086h_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN3901)
Plasmid#230386PurposeAiE0086h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cellsInsertSYFP2
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP13294 - pAAV-AiE0940m-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN3294)
Plasmid#230144PurposeAiE0940m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cellsDepositorInsertSYFP2-P2A-3XFLAG-10aa-H2B
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP15385: pAAV-AiE0873m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5385)
Plasmid#230875PurposeAiE0873m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic interneuronsInsertmScarlet
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceJan. 29, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP15747: pAAV-AiE0779m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5747)
Plasmid#230882PurposeAiE0779m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal direct pathway MSNs (D1-MSNs)InsertmScarlet
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceJan. 27, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP15745: pAAV-AiE0452h-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5745)
Plasmid#230880PurposeAiE0452h is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)InsertmScarlet
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceJan. 27, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-20nmEML-mRFP
Plasmid#231181PurposeExpresses a synthetic linker, tagged with mRFP, stabilizing the ER-mitochondrial distance at 20 nm from a lentiviral vectorDepositorInsert20nmEML-mRFP
UseLentiviralTagsExpressionMutationPromoterCMVAvailable sinceJan. 22, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (AAV Retrograde)
Viral Prep#125712-AAVrgPurposeReady-to-use AAV Retrograde particles produced from pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (#125712). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE plasmid DNA. CaMKIIa-driven expression of the optimized mosquito OPN3 rhodopsin in-frame with mScarlet. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.DepositorPromotershort version of αCamKinase II promoter (0.4kb)TagsNoneAvailable sinceJan. 8, 2025AvailabilityAcademic Institutions and Nonprofits only -
pET24a_SMOXdel
Plasmid#186785PurposeC-terminal His-Tag and a TEV cleaveage site, deletion of 8 residues (503-512) to transform into E. coli BL21 (DE3) cellsDepositorInsertSpermine oxidase (SMOX Human)
UseTagsHis tagExpressionBacterialMutationdeleted amino acids 503-512PromoterAvailable sinceOct. 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
LifeAct-scramble
Plasmid#217499PurposeExpresses LifeAct-mScarlet-scramble to serve as control plasmid for LifeAct-MTEDDepositorInsertLifeAct-mScarlet-scramble
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 3, 2024AvailabilityAcademic Institutions and Nonprofits only -
AiP15043 - pAAV-AiE1419m-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN5043)
Plasmid#224189PurposeAiE1419m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb+/Pthlh+ neuronsInsertSYFP2-P2A-3XFLAG-10aa-H2B
UseAAVTagsExpressionMutationPromoterAvailable sinceSept. 25, 2024AvailabilityAcademic Institutions and Nonprofits only -
pmCherry-Synaptojanin-1-145
Plasmid#223563PurposeExpresses the short isoform of SYNJ1 (neuronal) with mCherry tagged at the n-terminusDepositorInsertSYNJ1 (SYNJ1 Human)
UseTagsHis and mCherryExpressionMammalianMutationPromoterAvailable sinceSept. 9, 2024AvailabilityAcademic Institutions and Nonprofits only -
AiP13450: pAAV-AiE0140h-minBG-iCre-4X2C-WPRE3-BGHpA (Alias: CN3450)
Plasmid#214845PurposeExpression of iCre in striatal Pvalb neuronsInsertiCre
UseAAVTagsExpressionMutationPromoterAvailable sinceJuly 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA5-3xFLAG-SRSF1 siRNA-resitant
Plasmid#218974PurposeVector for expressing siRNA-resistant SRSF1 cDNA (siRNA sequence: CGUGGAGUUUGUACGGAAA)DepositorInsertSRSF1 cDNA
UseTagsExpressionMammalianMutationsiRNA-resistant SRSF1 cDNA (siRNA sequence: CGUGG…PromoterCMVAvailable sinceJune 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
pGP-CAG-iGABASnFR2n-WPRE-bGH-polyA
Plasmid#218869PurposeMammalian expression of improved GABA sensor (negative change in fluorescence)DepositorInsertiGABASnFR2n
UseTagsExpressionMammalianMutationS99A F104H R168PPromoterCAGAvailable sinceJune 5, 2024AvailabilityAcademic Institutions and Nonprofits only