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We narrowed to 29,354 results for: uros

Showing: 7521 - 7540 of 29354 results

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pAAV uN2C GFP (Ctl)

Plasmid

#224355

Purpose

Express GFP tagged upsteram ORF of NOTCH2NLC with a control size (12x) of GGC repeats

Depositor

Nicolas Charlet-Berguerand

Article

Boivin et al Neuron. 2021 Jun 2;109(11):1825-1835.e5.

Insert

uN2C

Use

AAV

Tags

eGFP

Expression

Mammalian

Mutation

Codon-optimized for expression in human, so no pu…

Promoter

CMV + chimeric intyron (CAG)

Available since

Oct. 7, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pDonor-FMR1-CGG-BsmBI

Plasmid

#222966

Purpose

0CGG with BsmBI site for inserting CGG repeats

Depositor

Xinyu Zhao

Article

Sirois et al Cell Rep. 2024 Jun 11;43(6):114330. doi:

Insert

FMR1 homologous template (no CGG repeats) with cloning site (FMR1 Human)

Use

CRISPR

Tags

Expression

Mutation

CGG repeats deleted from 5' UTR, BsmBI site …

Promoter

Available since

Sept. 16, 2024

Availability

Academic Institutions and Nonprofits only

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CIRTS-YTHDF2-Malat1

Plasmid

#216858

Purpose

CIRTS RNA targeting system for targeted knockdown of m6A-containing Malat1 at the synapse. CIRTS-YTHDF2-Calm3 and Malat1 gRNA is expressed under human Syn1 and U6 promoter, respectively.

Depositor

Timothy Bredy

Article

Madugalle et al J Neurosci. 2023 Oct 25;43(43):7084-7100

Insert

CIRTS-YTHDF2-Calm3-U6-Malat1 gRNA

Use

Lentiviral

Tags

GFP

Expression

Mammalian

Mutation

Promoter

Syn1, U6

Available since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only

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pHIV(T9)-DERA-sgresis

Plasmid

#222622

Purpose

Lentiviral vector that expresses sgRNA resistant DERA in mammalian cells

Depositor

Daniel Durocher

Article

Zhao et al Mol Cell. 2023 Aug 3;83(15):2792-2809.e9

Insert

DERA (DERA Human)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

EF1a

Available since

Aug. 19, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA5-FRT/T0-EGFP-GNB1L

Plasmid

#222621

Purpose

Mammalian expression vector of flag-tagged GNB1L

Depositor

Daniel Durocher

Article

Zhao et al Mol Cell. 2023 Aug 3;83(15):2792-2809.e9

Insert

GNB1L (GNB1L Human)

Use

Tags

EGFP

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Aug. 19, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pMMS22L-siR3

Plasmid

#221013

Purpose

mammalian expression vector of myc-Flag tagged MMS22L siRNA resistant

Depositor

Daniel Durocher

Article

O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

Insert

MMS22L (MMS22L Human)

Use

Tags

Flag and myc

Expression

Mammalian

Mutation

silent mutations MMS22L: 5'-aaAacGtgTtgCtgTg…

Promoter

CMV

Available since

July 31, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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CIRTS-FTO-Malat1

Plasmid

#216860

Purpose

CIRTS RNA targeting system for targeted removal of m6A on Malat1 at the synapse. CIRTS-FTO-Calm3 and Malat1 gRNA is expressed under human Syn1 and U6 promoter, respectively.

Depositor

Timothy Bredy

Article

Madugalle et al J Neurosci. 2023 Oct 25;43(43):7084-7100

Insert

CIRTS-FTO-Calm3-U6-Malat1 gRNA

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Syn1, U6

Available since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

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pMRX-IP-muGFP-hATG2A mLIRΔWIR

Plasmid

#215508

Purpose

Expresses GFP tagged human ATG2A which has the mutation in LC3 interacting region and lacks WIPI interacting region.

Depositor

Noboru Mizushima

Article

Shimizu et al Hum Mol Genet. 2023 Aug 7;32(16):2623-26

Insert

Autophagy related 2A (ATG2A Human)

Use

Retroviral

Tags

muGFP

Expression

Mammalian

Mutation

P656R (natural variant with no functional relevan…

Promoter

Available since

June 17, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2R)-NE

Plasmid

#215487

Purpose

Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

NE tag

Expression

Mammalian

Mutation

D (second aa) mutated to R

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2E)-NE

Plasmid

#215488

Purpose

Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

NE tag

Expression

Mammalian

Mutation

D (second aa) mutated to E

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2R)-GFP

Plasmid

#215490

Purpose

Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

EGFP

Expression

Mammalian

Mutation

D (second aa) mutated to R

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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FUW-hSNCA(D2E)-GFP

Plasmid

#215491

Purpose

Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

Depositor

Ophir Shalem

Article

Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

Insert

alpha-synuclein (SNCA Human)

Use

Lentiviral

Tags

EGFP

Expression

Mammalian

Mutation

D (second aa) mutated to E

Promoter

Ubc

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only

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ρ1-EM GABAA receptor in pEZT-BM

Plasmid

#213072

Purpose

Express human GABA-A rho1 receptor with truncated intracellular domain and superfolder GFP insertion in ICD

Depositor

Erik Lindahl

Article

Cowgill et al Neuron. 2023 Nov 1;111(21):3450-3464.e5.

Insert

Human GABAa rho1 receptor (GABRR1 Human)

Use

Bacmam, baculovirus, oocyte expression

Tags

Twin-Strep tag and superfolderGFP

Expression

Mammalian

Mutation

Encodes residues S58–L383 and D451–S479, separate…

Promoter

CMV and T7

Available since

Feb. 23, 2024

Availability

Academic Institutions and Nonprofits only

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Anti-Kv3.3 K+ channel [N375/67R]

Plasmid

#182113

Purpose

Mammalian Expression Plasmid of anti-Kv3.3 K+ channel (Mouse). Derived from hybridoma N375/67.

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Kv3.3 K+ channel (Mus musculus) recombinant mouse monoclonal antibody (Kcnc3 Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Dual CMV

Available since

Feb. 15, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV2ss-EFS-GFP-synPolyA-U6-sgHTT1-U6-sgCas9

Plasmid

#190903

Purpose

AAV-KamiCas9 vector expressing expressing thew GFP reporter gene and sgHTT and sgCas9

Depositor

Nicole Déglon

Article

Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

Insert

GFP, sgHTT and sgCas9 (HTT Human)

Use

AAV and CRISPR

Tags

Expression

Mutation

Promoter

EFS and U6

Available since

March 27, 2023

Availability

Academic Institutions and Nonprofits only

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Anti-Kv3.3 K+ channel [N375/67R]

Plasmid

#177537

Purpose

Mammalian Expression Plasmid of anti-Kv3.3 K+ channel (Mouse). Derived from hybridoma N375/67.

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Kv3.3 K+ channel (Mus musculus) recombinant mouse monoclonal antibody (Kcnc3 Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Dual CMV

Available since

May 17, 2022

Availability

Academic Institutions and Nonprofits only

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pCS2plus-mVenus1-155-GGGS-TDP43 M337V

Plasmid

#162612

Purpose

Allows for transcription of mVenus fluorophore half fused to mutant TDP-43-M337V for injection into zebrafish embryos for BiFC assays

Depositor

Marco Morsch

Article

Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

Insert

TARDBP (TARDBP Human)

Use

Tags

Expression

Mammalian

Mutation

M337V

Promoter

Available since

June 10, 2021

Availability

Academic Institutions and Nonprofits only

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pCS2plus-TDP-43 M337V

Plasmid

#162609

Purpose

Allows for transcription of mutant TDP-43-M337V mRNA for injection into zebrafish embryos for BiFC assays

Depositor

Marco Morsch

Article

Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

Insert

TARDBP (TARDBP Human)

Use

Tags

Expression

Mammalian

Mutation

M337V

Promoter

Available since

June 10, 2021

Availability

Academic Institutions and Nonprofits only

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pSOD1E133insTT-AcGFP1

Plasmid

#83441

Purpose

Expresses SOD1E133insTT in mammalian cells.

Depositor

Mohan Babu

Article

Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

Insert

SOD1 (SOD1 Human)

Use

Tags

AcGFP1

Expression

Mammalian

Mutation

E133insTT

Promoter

CMV

Available since

Nov. 9, 2016

Availability

Academic Institutions and Nonprofits only

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pSOD1E133Δ-AcGFP1

Plasmid

#83419

Purpose

Expresses SOD1E133Δ in mammalian cells.

Depositor

Mohan Babu

Article

Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

Insert

SOD1 (SOD1 Human)

Use

Tags

AcGFP1

Expression

Mammalian

Mutation

E133 deletion

Promoter

CMV

Available since

Nov. 9, 2016

Availability

Academic Institutions and Nonprofits only

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