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Plasmid#90213PurposeTo convert human skin fibroblasts into induced cholinergic neurons (hiCN) in combination with FGF2 and two small molecules, forskolin and dorsomorphin.DepositorUseRetroviralTagsExpressionMutationPromoterCMVAvailable sinceAug. 25, 2017AvailabilityAcademic Institutions and Nonprofits only
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pBrain-GFP-TACC3KDP(S558A)-shTACC3
Plasmid#59357PurposeExpresses GFP-tagged human TACC3 (RNAi-resistant) with S558A substitution and knocks down endogenous TACC3 via shRNA.DepositorInsertTransforming Acidic Coiled Coil protein 3 (TACC3 Human)
UseRNAiTagsGFPExpressionMammalianMutationSilent mutations in amino acids 30-33 to confer s…PromoterCMVAvailable sinceDec. 5, 2014AvailabilityAcademic Institutions and Nonprofits only -
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pCDF-rM1PYK
Plasmid#220232PurposeInducible expression of rabbit muscle pyruvate kinase isoform 1DepositorInsertRabbit muscle pyruvate kinase (PKM )
UseTags6xHis-MBP-SUMOExpressionBacterialMutationPromoterT7Available sinceAug. 1, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCDF-hLPYK
Plasmid#220231PurposeInducible expression of human liver pyruvate kinaseDepositorInsertHuman liver pyruvate kinase (PKLR Human)
UseTagsExpressionBacterialMutationPromoterT7Available sinceJuly 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
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TRIB3 gRNA (BRDN0001145861)
Plasmid#77199Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB3DepositorInsertTRIB3 (TRIB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRIB3 gRNA (BRDN0001147269)
Plasmid#77201Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB3DepositorInsertTRIB3 (TRIB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRIB3 gRNA (BRDN0001146247)
Plasmid#77202Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB3DepositorInsertTRIB3 (TRIB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRIB1 gRNA (BRDN0001162240)
Plasmid#76661Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB1DepositorInsertTRIB1 (TRIB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRIB1 gRNA (BRDN0001162480)
Plasmid#76662Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB1DepositorInsertTRIB1 (TRIB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRIB1 gRNA (BRDN0001162575)
Plasmid#76663Purpose3rd generation lentiviral gRNA plasmid targeting human TRIB1DepositorInsertTRIB1 (TRIB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only