168,238 results

1. LV-TRE-VP64 human MyoD-T2A-dsRedExpress2

   Plasmid

   #60629

   Purpose

   Expresses VP64 human MyoD and dsRedExpress2 in response to doxycycline

   Depositor

   Charles Gersbach

   Article

   Kabadi et al ACS Synth Biol. 2014 Dec 10.

   Insert

   VP64 human MyoD (MYOD1 Human)
   

   Use

   Lentiviral

   Promoter

   TRE

   Available Since

   Dec. 11, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

   Pooled Library

   #84003

   Purpose

   Mouse CRISPRa Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

3. pcDNA3-myc-RIG-I

   Plasmid

   #240814

   Purpose

   Expresses myc-tagged RIG-I in mammalian cells

   Depositor

   AJ te Velthuis

   Insert

   RIG-I (RIGI Human)
   

   Tags

   Myc

   Expression

   Mammalian

   Available Since

   Aug. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. TRE-mCherry

   Plasmid

   #92202

   Purpose

   Fluorescent protein reporter construct

   Depositor

   Alice Ting

   Article

   Wang et al Nat Biotechnol. 2017 Jun 26. doi: 10.103

   Insert

   mCherry
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   TRE

   Available Since

   June 16, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. TDP-43_NTD1-80_E17R

   Plasmid

   #104479

   Purpose

   bacterial expression of TDP-43 NTD E17R

   Depositor

   Nicolas Fawzi

   Article

   Wang et al EMBO J. 2018 Mar 1;37(5). pii: embj.2017

   Insert

   TDP-43 (TARDBP Human)
   

   Tags

   His

   Expression

   Bacterial

   Mutation

   E17R

   Available Since

   March 20, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-CAG-tdTomato (codon diversified) (AAV PHP.eB)

   Viral Prep

   #59462-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pAAV-CAG-tdTomato (codon diversified) (#59462). In addition to the viral particles, you will also receive purified pAAV-CAG-tdTomato (codon diversified) plasmid DNA. CAG-driven tdTomato expression control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Promoter

   CAG

   Tags

   tdTomato (codon diversified)

   Available Since

   Feb. 28, 2018

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-CaMKIIa-hM3D(Gq)-mCherry

   Plasmid

   #50476

   Purpose

   Gq-coupled hM3D DREADD fused with mCherry under the control of CaMKIIa promoter

   Depositor

   Bryan Roth

   Has Service

   AAV1, AAV2, AAV5, AAV8, and AAV9

   Insert

   hM3D(Gq)-mCherry (CHRM3 Human)
   

   Use

   AAV

   Tags

   mCherry

   Mutation

   See supplemental documents for DREADD mutations

   Promoter

   CaMKIIa

   Available Since

   April 16, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. pScaffold-H1 donor

   Plasmid

   #118152

   Purpose

   PCR template for dual guide RNA cloning, guide RNA scaffold for the Streptococcus pyogenes CRISPR/Cas9 system - H1 promoter

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Type

   Empty backbone

   Expression

   Mammalian

   Available Since

   July 24, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. 4xM67 pTATA TK-Luc

   Plasmid

   #8688

   Depositor

   Jim Darnell

   Article

   Besser et al Mol Cell Biol 1999 Feb;19(2):1401-9.

   Insert

   4 repeated M67 sites
   

   Use

   Luciferase

   Expression

   Mammalian

   Available Since

   July 18, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLenti_EF1a_EV

    Plasmid

    #183116

    Purpose

    Empty vector control for pLenti_EF1a constructs

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    Small multiple cloning site
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHR-TRE3G-dCas9-HaloTag

    Plasmid

    #169448

    Purpose

    expression of dCas9-HaloTag

    Depositor

    Stanley Qi

    Article

    Wang et al Cell. 2018 Nov 15;175(5):1405-1417.e14.

    Insert

    dCas9-HaloTag
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    June 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-Ef1a-DIO ChETA-EYFP (AAV1)

    Viral Prep

    #26968-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-DIO ChETA-EYFP (#26968). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO ChETA-EYFP plasmid DNA. EF1a-driven, Cre-dependent, ChETA fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Gunaydin et al Nat Neurosci. 2010 Mar;13(3):387-92. doi

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available Since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pAAV.Syn.GCaMP6m.WPRE.SV40 (AAV9)

    Viral Prep

    #100841-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.Syn.GCaMP6m.WPRE.SV40 (#100841). In addition to the viral particles, you will also receive purified pAAV.Syn.GCaMP6m.WPRE.SV40 plasmid DNA. Syn-driven GCaMP6m calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

    Promoter

    Syn

    Available Since

    April 17, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pcDNA3 HA Arf1

    Plasmid

    #10830

    Depositor

    Thomas Roberts

    Article

    Furman et al J Biol Chem. 2002 Mar 8. 277(10):7962-9.

    Insert

    Arf1 (ARF1 Bovine)
    

    Tags

    HA

    Expression

    Mammalian

    Available Since

    Jan. 5, 2006

    Availability

    Academic Institutions and Nonprofits only

15. pEGFP-hGal3

    Plasmid

    #73080

    Purpose

    Expression in mammalian cells

    Depositor

    Tamotsu Yoshimori

    Article

    Maejima et al EMBO J. 2013 Aug 28;32(17):2336-47. doi:

    Insert

    Galectin-3 (LGALS3 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 11, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLV-puro-N-Flag-h-SNRNP40

    Plasmid

    #134254

    Purpose

    Lentivector encoding Flag-tagged human SNRNP40

    Depositor

    Bruce Beutler

    Article

    Zhang et al Nat Immunol. 2019 Oct;20(10):1322-1334.

    Insert

    SNRP40 (SNRNP40 Human)
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    May 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCRISPRa_all-in-one

    Plasmid

    #183695

    Purpose

    Expresses CRISPRa components including dCas9-VP64, Synergistic Activation Mediators (SAM), mCherry, and gRNA expression cassette, blasticidin selective

    Depositor

    Edward Avezov

    Article

    Melo et al Nat Commun. 2022 May 6;13(1):2501. doi:

    Type

    Empty backbone

    Use

    CRISPR

    Available Since

    April 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. lenti-mito-mTagBFP2

    Plasmid

    #216130

    Purpose

    Lentiviral vector for expressing mTagBFP2 localizing to mitochondria.

    Depositor

    Stefan Kubicek

    Article

    Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

    Insert

    EF1a-COX8AmitochondrialLocalizationSignal-mTagBFP2-WPRE
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCW-Flag-CtIP

    Plasmid

    #71108

    Purpose

    mammalian expession of Flag-CtlP

    Depositor

    Daniel Durocher

    Article

    Orthwein et al Nature. 2015 Dec 9. doi: 10.1038/nature1

    Insert

    CtlP
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Please see Depositor Comments

    Promoter

    TRE promoter, Tet ON

    Available Since

    Nov. 11, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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20. pMH-HA

    Plasmid

    #101767

    Purpose

    Gateway-compatible destination vector for mammalian expression of N-terminal HA-tag fusion protein

    Depositor

    Michael Huen

    Article

    An et al Proc Natl Acad Sci U S A. 2017 Apr 4;114

    Type

    Empty backbone

    Tags

    HA

    Expression

    Mammalian

    Available Since

    Oct. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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