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Plasmid#82748PurposeGateway Donor vector containing FAM173B, part of the Target Accelerator Plasmid Collection.DepositorInsertFAM173B (FAM173B Human)
UseGateway entry vectorTagsExpressionMutationT75M; R187PPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_GPR137B_p.Y135N
Plasmid#82752PurposeGateway Donor vector containing GPR137B, part of the Target Accelerator Plasmid Collection.DepositorInsertGPR137B (GPR137B Human)
UseGateway entry vectorTagsExpressionMutationY135NPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_CCND1_p.E172K
Plasmid#82733PurposeGateway Donor vector containing CCND1, part of the Target Accelerator Plasmid Collection.DepositorInsertCCND1 (CCND1 Human)
UseGateway entry vectorTagsExpressionMutationE172KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB5_p.I159S
Plasmid#82734PurposeGateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB5 (SERPINB5 Human)
UseGateway entry vectorTagsExpressionMutationI159S; S176P; p.190_192delTDTins25amino acids; p.…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB5_p.D141A
Plasmid#82735PurposeGateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB5 (SERPINB5 Human)
UseGateway entry vectorTagsExpressionMutationp. D141A; p. 176S>P; p.190_192delTDTins25amino…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB5_p.A7T
Plasmid#82736PurposeGateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB5 (SERPINB5 Human)
UseGateway entry vectorTagsExpressionMutationp. A7T; p.176S>P; p. 190_192delTDTins25; p.194…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB5_p.A42F
Plasmid#82738PurposeGateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB5 (SERPINB5 Human)
UseGateway entry vectorTagsExpressionMutationp.A42F; p.176S>P; p.190_192delTDTins25; p.194_…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SERPINB5_p.A165T
Plasmid#82741PurposeGateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.DepositorInsertSERPINB5 (SERPINB5 Human)
UseGateway entry vectorTagsExpressionMutationp. A165T; p.176S>P; p.190_192delTDTins25; p.19…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_HAVCR2_p.P6S
Plasmid#82742PurposeGateway Donor vector containing HAVCR2, part of the Target Accelerator Plasmid Collection.DepositorInsertHAVCR2 (HAVCR2 Human)
UseGateway entry vectorTagsExpressionMutationp.P6S; p.R140LPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pET-Duet-ECHA(37-763) K351R-FLAG (no His-tag)
Plasmid#96888Purposeexpresses-flag tagged mouse ECHA(37-768) K351R in E.coli cells (no His-tag)DepositorInsertTrifunctional enzyme subunit alpha, mitochondrial (Hadha Mouse)
UseTagsFLAG-taggedExpressionBacterialMutationdeleted amino acid 1-36, mutated lysine 351 to ar…PromoterT7Available sinceAvailabilityAcademic Institutions and Nonprofits only -
pU6-pegRNA-LRRK2-G2019S-3b
Plasmid#180433PurposeTransiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cellsDepositorInsertncRNA targeting LRRK2-G2019S (LRRK2 Human)
UseCRISPRTagsExpressionMammalianMutationLRRK2-G2019SPromoterU6Available sinceAvailabilityAcademic Institutions and Nonprofits only -
pU6-pegRNA-LRRK2-G2019S-3c
Plasmid#180434PurposeTransiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cellsDepositorInsertncRNA targeting LRRK2-G2019S (LRRK2 Human)
UseCRISPRTagsExpressionMammalianMutationLRRK2-G2019SPromoterU6Available sinceAvailabilityAcademic Institutions and Nonprofits only -
pU6-pegRNA-LRRK2-G2019S-3d
Plasmid#180435PurposeTransiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cellsDepositorInsertncRNA targeting LRRK2-G2019S (LRRK2 Human)
UseCRISPRTagsExpressionMammalianMutationLRRK2-G2019SPromoterU6Available sinceAvailabilityAcademic Institutions and Nonprofits only -
Px330-EGFP-LRRK2-CRISPR/Cas9
Plasmid#180437PurposePlasmid to express Cas9 from S.pyogenesand CRISPR gRNA to introduce LRRK2-G2019S mutation in human cellsDepositorInsertgRNA targeting LRRK2-G2019S (LRRK2 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterU6Available sinceAvailabilityAcademic Institutions and Nonprofits only -
Mouse metabolism knockout library
Pooled Library#160129PurposeCRISPR library targets mouse metabolic genesDepositorExpressionMammalianSpeciesMus musculusUseCRISPR and LentiviralAvailable sinceNov. 10, 2020AvailabilityAcademic Institutions and Nonprofits only -
Mouse lipid metabolism knockout library
Pooled Library#206248PurposeThe lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.DepositorUseCRISPR and LentiviralAvailable sinceAug. 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pUCmini-iCAP-AAV9-X1.1
Plasmid#196836Purposenon-standard AAV2 rep-AAV9-X1.1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification systemDepositorInsertSynthetic construct isolate AAV9-X1.1 VP1 gene
UseAAVTagsExpressionMammalianMutationPromoterp41Available sinceJune 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pUCmini-iCAP-AAV.CAP-Mac
Plasmid#200658PurposeSynthetic construct isolate AAV.CAP-Mac VP1 geneDepositorInsertSynthetic construct isolate AAV.CAP-Mac VP1 gene
UseAAVTagsExpressionMammalianMutation7 amino acid insertion after Q588 of the AAV9 CAP…Promoterp41Available sinceAug. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pLV-TRE3G-YAP1-5SA-CMV-mCherry-T2A-Puro
Plasmid#176851Purposelentiviral vector for doxycycline-inducible YAP1 5SA constitutively active expressionDepositorInserthYAP1-5SA (YAP1 Human)
UseLentiviralTagsExpressionMutationS61A, S109A, S127A, S164A, S381A (phosphorylation…PromoterAvailable sinceNov. 5, 2021AvailabilityAcademic Institutions and Nonprofits only -
AAV-pCbh-SpRY[C-term]-gRNAentry (CA20)
Plasmid#197511PurposeCbh promoter expression plasmid for C-terminal intein-split AAV construct with C-term of SpRY and BsmBI entry cassette to clone SpCas9 gRNA spacerDepositorInsertAAV-[ITR]-pCbh-BPNLS-NpuC-SpRY[C-term]-BPNLS-gRNA[BsmBI]-pU6-[ITR]
UseAAV and CRISPRTagsBPNLS and BPNLS-NpuC(intein)ExpressionMutationC-terminal mutations of SpRY(L1111R/D1135L/S1136W…PromoterCbhAvailable sinceMarch 6, 2023AvailabilityAcademic Institutions and Nonprofits only