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Plasmid#140740PurposeLentiviral vector to overexpress the autism-associated PTEN mutation F241S and GFP as two separate proteinsDepositorInsertGFP-T2A-PTENF241S (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationF241SPromoterhUbiCAvailable sinceMay 4, 2020AvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-W274L
Plasmid#140742PurposeLentiviral vector to overexpress the autism-associated PTEN mutation W274L and GFP as two separate proteinsDepositorInsertGFP-T2A-PTENW274L (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationW274LPromoterhUbiCAvailable sinceMay 4, 2020AvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-D252G
Plasmid#140741PurposeLentiviral vector to overexpress the autism-associated PTEN mutation D252G and GFP as two separate proteinsDepositorInsertGFP-T2A-PTEND252G (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationD252GPromoterhUbiCAvailable sinceMay 4, 2020AvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-H93R
Plasmid#140739PurposeLentiviral vector to overexpress the autism-associated PTEN mutation H93R and GFP as two separate proteinsDepositorInsertGFP-T2A-PTENH93R (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationH93RPromoterhAvailable sinceMay 4, 2020AvailabilityAcademic Institutions and Nonprofits only -
psiCHECK2-miR-200b-3p
Plasmid#135694PurposeMammalian expression vector, Luciferase reporter to test activity of miRNA (miR-200b)DepositorInsertmiR-200b from human PTEN 3'UTR
UseTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 16, 2021AvailabilityAcademic Institutions and Nonprofits only -
psiCHECK2-miR-26b-5p
Plasmid#135695PurposeMammalian expression vector, Luciferase reporter to test activity of miRNA (miR-26b)DepositorInsertmiR-26b from human PTEN 3'UTR
UseTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 16, 2021AvailabilityAcademic Institutions and Nonprofits only -
pCMV-DnpK
Plasmid#71403PurposeExpresses tRNA and synthetases for mammalian encoding of a dinitrophenyl hapten, DnpKDepositorInsertaminoacyl-tRNA synthetase
UseTagsExpressionMammalianMutationY271M,L274T,C313A, and Y349FPromoterCMVAvailable sinceFeb. 16, 2016AvailabilityAcademic Institutions and Nonprofits only -
pVAX1/mTyr-Cre
Plasmid#99249PurposeExpresses Cre recombinase under tyrosinase promoterDepositorInsertsCre recombinase
mTyr enh/prom
UseTagsMycExpressionMammalianMutationPromoterAvailable sinceDec. 8, 2017AvailabilityAcademic Institutions and Nonprofits only -
pPHAGE-CR-PINK1-C-TAP
Plasmid#128510PurposeLentiviral constitutive expression of CRISPR-resistant PINK1 with c-terminal FLAG and HA tag.DepositorInsertPTEN induced kinase 1 (PINK1 Human)
UseLentiviralTagsFLAG and HA tagsExpressionMammalianMutationSynonymous silent mutation in Q5 to render sgRNA …PromoterCMVAvailable sinceSept. 16, 2019AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-PINK1
Plasmid#23504DepositorInsertPINK1 (PINK1 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
TPTE_pCSdest
Plasmid#53788DepositorInsertTPTE (TPTE Human)
UseTagsExpressionMammalianMutationPromoterSP6 and CMVAvailable sinceMarch 27, 2018AvailabilityIndustry, Academic Institutions, and Nonprofits -
pDONR223_TPTE_WT
Plasmid#81867PurposeGateway Donor vector containing TPTE , part of the Target Accelerator Plasmid Collection.DepositorInsertTPTE (TPTE Human)
UseGateway entry vectorTagsExpressionMutationL452PPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
Target Accelerator Pan-Cancer Mutant Collection
Plasmid Kit#1000000103PurposePanel of cancer alleles that have undergone basic, functional screening; full-length, human clones (454 mutant and 177 corresponding wild-type) in the Gateway cloning systemDepositorAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
Target Accelerator Lung Cancer Mutant Collection
Plasmid Kit#1000000104PurposePanel of lung adenocarcinoma alleles that have undergone basic, functional screening; full-length human clones (180 mutant and 45 corresponding wild-type) and 82 wild-type experssion controlsDepositorAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
RAS Pathway 2.0 Clone Collection
Plasmid Kit#1000000070PurposeCollection contains 180 genes in the âRAS pathway version 2.0â, a crowdsourced pathway map of the RAS signaling pathway; For use with Gateway cloning or FNLCR Combinatorial Cloning PlatformDepositorAvailable sinceMarch 1, 2016AvailabilityAcademic Institutions and Nonprofits only -
Target Accelerator Genetic Pathway Reference Set
Plasmid Kit#1000000105PurposeCollection of genes and mutations for reference pathway signatures and phenotypes to compare with those derived from cancer alleles; represent over 25 cellular signaling pathways and processesDepositorAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only