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Plasmid#186023Purposeknock out DHODH in mammalian cellsDepositorInsertDihydroorotate Dehydrogenase (Quinone) (DHODH Human)
UseCRISPR and LentiviralTagsExpressionMutationPromoterU6Available sinceJune 21, 2022AvailabilityAcademic Institutions and Nonprofits only -
pMIR-CDH1 mutUTR
Plasmid#25039DepositorInsertCDH1 mutant 3'UTR (CDH1 Human)
UseLuciferaseTagsExpressionMammalianMutationsubstitution of 6nt within the miR-9 binding site…PromoterAvailable sinceJune 7, 2010AvailabilityAcademic Institutions and Nonprofits only -
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sgRNA BRCA2 R2842C
Plasmid#139324PurposePlasmid expressing a sgRNA to introduce BRCA2 R2842C using base editingDepositorInsertsgRNA to insert BRCA2 R2842C using base editing
UseTagsExpressionMammalianMutationPromoterU6Available sinceMay 22, 2020AvailabilityAcademic Institutions and Nonprofits only -
ZAP70 gRNA (BRDN0001148252)
Plasmid#77955Purpose3rd generation lentiviral gRNA plasmid targeting human ZAP70DepositorInsertZAP70 (ZAP70 )
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pAAV-MCS-shCHD5 #1
Plasmid#68876PurposeCHD5 shRNA expressed from Adeno-associated viral (AAV) vectorDepositorInsertCHD5
UseAAV and RNAiTagsExpressionMammalianMutationPromoterH1Available sinceSept. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
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pLKO.1P MUTYH_1
Plasmid#160785PurposeSuppress MUTYHDepositorInsertshMUTYH_1
UseLentiviralTagsExpressionMutationPromoterAvailable sinceOct. 29, 2020AvailabilityAcademic Institutions and Nonprofits only -
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pMCB320-sgNC.SPA
Plasmid#169834PurposeExpresses a negative control sgRNADepositorInsertsafe harbor sgRNA
UseCRISPR, Lentiviral, and Mouse TargetingTagsExpressionMammalianMutationPromotermU6Available sinceJune 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
pMCB320-sgNC.ACOCA
Plasmid#169836PurposeExpresses a negative control sgRNADepositorInsertsafe harbor sgRNA
UseCRISPR, Lentiviral, and Mouse TargetingTagsExpressionMammalianMutationPromotermU6Available sinceJune 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
MO70-hJunctate - EF-mutant
Plasmid#79597PurposeTransient and retroviral expressionDepositorInsertjunctate (ASPH Human)
UseRetroviralTagsFLAGExpressionMammalianMutation77DAD79 to 77AAA79PromoterCMVAvailable sinceAug. 17, 2016AvailabilityAcademic Institutions and Nonprofits only -
ROR1 gRNA (BRDN0001162245)
Plasmid#76043Purpose3rd generation lentiviral gRNA plasmid targeting human ROR1DepositorInsertROR1 (ROR1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
STK36 gRNA (BRDN0001145146)
Plasmid#77276Purpose3rd generation lentiviral gRNA plasmid targeting human STK36DepositorInsertSTK36 (STK36 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
STK36 gRNA (BRDN0001148669)
Plasmid#77277Purpose3rd generation lentiviral gRNA plasmid targeting human STK36DepositorInsertSTK36 (STK36 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
ROR1 gRNA (BRDN0001145812)
Plasmid#76045Purpose3rd generation lentiviral gRNA plasmid targeting human ROR1DepositorInsertROR1 (ROR1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pLenti CRISPR V2 sgShmt2_1
Plasmid#106314PurposeExpress Cas9 and sgRNA targeting mShmt2DepositorInsertsgRNA targeting SHMT2 (Shmt1 Mouse)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterAvailable sinceApril 27, 2018AvailabilityAcademic Institutions and Nonprofits only -
ULK2 gRNA (BRDN0001145025)
Plasmid#77261Purpose3rd generation lentiviral gRNA plasmid targeting human ULK2DepositorInsertULK2 (ULK2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pX330-Utf1 gRNA
Plasmid#128842PurposegRNA for targeting mouse Utf1 locus using CRISPR-cas techniqueDepositorInsertUtf1 gRNA (Utf1 Mouse)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceAug. 27, 2019AvailabilityAcademic Institutions and Nonprofits only