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The pathogenic E139D mutation stabilizes a non-canonical active state of the multi-domain phosphatase SHP2.

van Vlimmeren AE, Jiang Z, Karandur D, Applebaum Licht AT, Shah NH
bioRxiv [Preprint]. 2025 Jul 4:2025.07.02.662799. doi: 10.1101/2025.07.02.662799. (Link opens in a new window) PubMed (Link opens in a new window) Article

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