Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2.
Raig ND, Surridge KJ, Sanz-Murillo M, Dederer V, Kramer A, Schwalm MP, Elson L, Chatterjee D, Mathea S, Hanke T, Leschziner AE, Reck-Peterson SL, Knapp S
bioRxiv [Preprint]. 2025 Feb 13:2024.09.17.613365. doi: 10.1101/2024.09.17.613365.
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Plasmids from this article have been deposited by multiple labs. See below for all materials from each lab:
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 228879 | pFB-EPCP5 | Expression of Z-tagged LRRK2 KW using Baculoviruses |
| 228880 | pET28A-Rab8A | Expression of His-tagged Rab8A in E. coli |
| 231174 | pcDNA5 FRT TO GFP11-LRRK2 | Expresses GFP-11-LRRK2 (wildtype, full length) in mammalian cells |
| 231175 | pcDNA5 FRT TO GFP11-LRRK2_G2019S | Expresses GFP-11-LRRK2 G2019S in mammalian cells |