PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein.

Johnson SM, Bao H, McMahon CE, Chen Y, Burr SD, Anderson AM, Madeyski-Bengtson K, Linden D, Han X, Liu J
Nat Commun. 2024 Jun 6;15(1):4847. doi: 10.1038/s41467-024-49224-x. PubMed Article

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