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The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity.

Prasad CB, Oo A, Liu Y, Qiu Z, Zhong Y, Li N, Singh D, Xin X, Cho YJ, Li Z, Zhang X, Yan C, Zheng Q, Wang QE, Guo D, Kim B, Zhang J
Nat Commun. 2024 May 31;15(1):4667. doi: 10.1038/s41467-024-48076-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

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