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The hinge-engineered IgG1-IgG3 hybrid subclass IgGh(47) potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.

Izadi A, Karami Y, Bratanis E, Wrighton S, Khakzad H, Nyblom M, Olofsson B, Happonen L, Tang D, Sundwall M, Godzwon M, Chao Y, Toledo AG, Schmidt T, Ohlin M, Nilges M, Malmstrom J, Bahnan W, Shannon O, Malmstrom L, Nordenfelt P
Nat Commun. 2024 Apr 27;15(1):3600. doi: 10.1038/s41467-024-47928-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

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