Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis.
Zong Z, Xie F, Wang S, Wu X, Zhang Z, Yang B, Zhou F
Cell. 2024 May 9;187(10):2375-2392.e33. doi: 10.1016/j.cell.2024.04.002. Epub 2024 Apr 22.
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