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Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.

Radko-Juettner S, Yue H, Myers JA, Carter RD, Robertson AN, Mittal P, Zhu Z, Hansen BS, Donovan KA, Hunkeler M, Rosikiewicz W, Wu Z, McReynolds MG, Roy Burman SS, Schmoker AM, Mageed N, Brown SA, Mobley RJ, Partridge JF, Stewart EA, Pruett-Miller SM, Nabet B, Peng J, Gray NS, Fischer ES, Roberts CWM
Nature. 2024 Apr;628(8007):442-449. doi: 10.1038/s41586-024-07250-1. Epub 2024 Mar 27. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
249181pHoY108_pAC8_hsDCAF5_1-477Express DCAF5(1-477) in Insect cells
249182pHoY109_pAC8_hsDCAF5_1-601Express DCAF5(1-601) in Insect cells
249183pHoY110_pAC8_hsDCAF5_FLExpress DCAF5(full length) in Insect cells

Antibodies from Article