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Engineered FSHD mutations results in D4Z4 heterochromatin disruption and feedforward DUX4 network activation.

Kong X, Nguyen NV, Li Y, Sakr JS, Williams K, Sharifi S, Chau J, Bayrakci A, Mizuno S, Takahashi S, Kiyono T, Tawil R, Mortazavi A, Yokomori K
iScience. 2024 Feb 29;27(4):109357. doi: 10.1016/j.isci.2024.109357. eCollection 2024 Apr 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

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