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Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.

Belle R, Sarac H, Salah E, Bhushan B, Szykowska A, Roper G, Tumber A, Kriaucionis S, Burgess-Brown N, Schofield CJ, Brown T, Kawamura A
J Med Chem. 2024 Mar 28;67(6):4525-4540. doi: 10.1021/acs.jmedchem.3c01820. Epub 2024 Jan 31. (Link opens in a new window) PubMed (Link opens in a new window) Article

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