Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription.

Lau MS, Hu Z, Zhao X, Tan YS, Liu J, Huang H, Yeo CJ, Leong HF, Grinchuk OV, Chan JK, Yan J, Tee WW
Nat Commun. 2023 Oct 13;14(1):6464. doi: 10.1038/s41467-023-42078-9. PubMed Article

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