DNA topoisomerase 1 represses HIV-1 promoter activity through its interaction with a guanine quadruplex present in the LTR sequence.
Lista MJ, Jousset AC, Cheng M, Saint-Andre V, Perrot E, Rodrigues M, Di Primo C, Gadelle D, Toccafondi E, Segeral E, Berlioz-Torrent C, Emiliani S, Mergny JL, Lavigne M
Retrovirology. 2023 May 30;20(1):10. doi: 10.1186/s12977-023-00625-8.
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