MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex.

Branch MR, Hsu CL, Ohnishi K, Shen WC, Lee E, Meisenhelder J, Winborn B, Sopher BL, Taylor JP, Hunter T, La Spada AR
Life Sci Alliance. 2023 May 23;6(8):e202201525. doi: 10.26508/lsa.202201525. Print 2023 Aug. PubMed Article

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