Deleting specific residues from the HNH linkers creates a CRISPR-SpCas9 variant with high fidelity and efficiency.
Wang G, Wang C, Chu T, Wu X, Anderson CM, Huang D, Li J
J Biotechnol. 2023 May 20;368:42-52. doi: 10.1016/j.jbiotec.2023.04.008. Epub 2023 Apr 26.
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