Nonspecific interactions between Cas12a and dsDNA located downstream of the PAM mediate target search and assist AsCas12a for DNA cleavage.

Sun R, Zhao Y, Wang W, Liu JG, Chen C
Chem Sci. 2023 Mar 10;14(14):3839-3851. doi: 10.1039/d2sc05463a. eCollection 2023 Apr 5. PubMed Article

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