Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.

Imre G, Takacs B, Czipa E, Drubi AB, Jaksa G, Latinovics D, Nagy A, Karkas R, Hudoba L, Vasarhelyi BM, Pankotai-Bodo G, Blastyak A, Hegedus Z, German P, Balint B, Ahmed Abdullah KS, Kopasz AG, Kovacs A, Nagy LG, Sukosd F, Pinter L, Rulicke T, Barta E, Nagy I, Haracska L, Mates L
Mol Ther Methods Clin Dev. 2023 Mar 14;29:145-159. doi: 10.1016/j.omtm.2023.03.003. eCollection 2023 Jun 8. PubMed Article

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