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Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer.

Liu J, Zhang C, Zhang T, Chang CY, Wang J, Bazile L, Zhang L, Haffty BG, Hu W, Feng Z
Nat Metab. 2022 Dec;4(12):1830-1846. doi: 10.1038/s42255-022-00708-4. Epub 2022 Dec 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

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