Natural Nucleoside Modifications in Guide RNAs Can Modulate the Activity of the CRISPR-Cas9 System In Vitro.

Prokhorova DV, Vokhtantsev IP, Tolstova PO, Zhuravlev ES, Kulishova LM, Zharkov DO, Stepanov GA
CRISPR J. 2022 Dec;5(6):799-812. doi: 10.1089/crispr.2022.0069. Epub 2022 Nov 9. PubMed Article

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