Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection.

Yang J, Song Y, Deng X, Vanegas JA, You Z, Zhang Y, Weng Z, Avery L, Dieckhaus KD, Peddi A, Gao Y, Zhang Y, Gao X
Nat Chem Biol. 2022 Sep 22. pii: 10.1038/s41589-022-01135-y. doi: 10.1038/s41589-022-01135-y. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
193020	RBD#3L	hnRNP A1 RRM2 RNA binding domain inserted in between N415 and N416 of Loop 1 of LwaCas13a
193021	RBD#4L	hnRNP C RRM RNA binding domain inserted in between N415 and N416 of Loop 1 of LwaCas13a