Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast.

Caudal E, Friedrich A, Jallet A, Garin M, Hou J, Schacherer J
Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2204206119. doi: 10.1073/pnas.2204206119. Epub 2022 Sep 6. PubMed Article

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