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Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Burli RW, Rubinsztein DC
Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. (Link opens in a new window) PubMed (Link opens in a new window) Article

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