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RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

Fang L, Ford-Roshon D, Russo M, O'Brien C, Xiong X, Gurjao C, Grandclaudon M, Raghavan S, Corsello SM, Carr SA, Udeshi ND, Berstler J, Sicinska E, Ng K, Giannakis M
Nat Commun. 2022 Jun 8;13(1):3181. doi: 10.1038/s41467-022-30794-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

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