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A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling.

Wu CH, Tatavarty V, Jean Beltran PM, Guerrero AA, Keshishian H, Krug K, MacMullan MA, Li L, Carr SA, Cottrell JR, Turrigiano GG
Elife. 2022 Apr 26;11. pii: 74277. doi: 10.7554/eLife.74277. (Link opens in a new window) PubMed (Link opens in a new window) Article

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