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A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cellsurface proteins on target cells.

Aoyama S, Yasuda S, Li H, Watanabe D, Umezawa Y, Okada K, Nogami A, Miura O, Kawamata N
Int J Mol Med. 2022 Apr;49(4). pii: 42. doi: 10.3892/ijmm.2022.5097. Epub 2022 Feb 4. (Link opens in a new window) PubMed (Link opens in a new window) Article

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