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In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4(+) TH1 cell response.

Sutra Del Galy A, Menegatti S, Fuentealba J, Lucibello F, Perrin L, Helft J, Darbois A, Saitakis M, Tosello J, Rookhuizen D, Deloger M, Gestraud P, Socie G, Amigorena S, Lantz O, Menger L
Sci Immunol. 2021 Dec 3;6(66):eabe8219. doi: 10.1126/sciimmunol.abe8219. Epub 2021 Dec 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

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