Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1alpha proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90.
Zhao S, Zhou L, Dicker DT, Lev A, Zhang S, Ross E, El-Deiry WS
Sci Rep. 2021 Oct 22;11(1):20871. doi: 10.1038/s41598-021-00150-8.
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