The AKT modulator A-443654 reduces alpha-synuclein expression and normalizes ER stress and autophagy.
Gandelman M, Dansithong W, Kales SC, Paul S, Maag G, Aoyama E, Zakharov A, Rai G, Dexheimer T, Whitehill BM, Sun H, Jadhav A, Simeonov A, Henderson MJ, Huynh DP, Pulst SM, Scoles DR
J Biol Chem. 2021 Oct;297(4):101191. doi: 10.1016/j.jbc.2021.101191. Epub 2021 Sep 11.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
No plasmids are currently publicly available from Addgene for this article.