Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases.
Jang H, Jo DH, Cho CS, Shin JH, Seo JH, Yu G, Gopalappa R, Kim D, Cho SR, Kim JH, Kim HH
Nat Biomed Eng. 2021 Aug 26. pii: 10.1038/s41551-021-00788-9. doi: 10.1038/s41551-021-00788-9.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 176649 | TS-PE2-N | Expresses N-terminus of PE2 in mammalian cells |
| 176650 | TS-PE2-C-WPRE | Expresses C-terminus of PE2 in mammalian cells |
| 176901 | U6-pegRNA-H1-nick sgRNA-mCherry | Expresses prime editing guide RNA and guide RNA in mammalian cells |
| 176933 | pLenti-NG-PE2-BSD | Expresses PE2-NG variant in mammalian cells |