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Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease.

Tong BC, Wu AJ, Huang AS, Dong R, Malampati S, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Zhu Z, Su C, Liu J, Song J, Lu JH, Tan J, Pan W, Li M, Cheung KH
Autophagy. 2022 Mar;18(3):624-642. doi: 10.1080/15548627.2021.1945220. Epub 2021 Jul 27. (Link opens in a new window) PubMed (Link opens in a new window) Article

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