Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
Milligan JC, Zeisner TU, Papageorgiou G, Joshi D, Soudy C, Ulferts R, Wu M, Lim CT, Tan KW, Weissmann F, Canal B, Fujisawa R, Deegan T, Nagaraj H, Bineva-Todd G, Basier C, Curran JF, Howell M, Beale R, Labib K, O'Reilly N, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2499-2515. doi: 10.1042/BCJ20210197.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169177 | pLIB_3xFlag-His-nsp5CS-nsp9 (SARS-CoV-2) | Baculoviral transfer vector to express SARS-CoV-2 nsp9 with nsp5-cleavable 3xFlag-His6 tag in insect cells |