RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha3 allosteric site.

Haza KZ, Martin HL, Rao A, Turner AL, Saunders SE, Petersen B, Tiede C, Tipping K, Tang AA, Ajayi M, Taylor T, Harvey M, Fishwick KM, Adams TL, Gaule TG, Trinh CH, Johnson M, Breeze AL, Edwards TA, McPherson MJ, Tomlinson DC
Nat Commun. 2021 Jun 30;12(1):4045. doi: 10.1038/s41467-021-24316-0. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.