Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development.

Espinola SM, Gotz M, Bellec M, Messina O, Fiche JB, Houbron C, Dejean M, Reim I, Cardozo Gizzi AM, Lagha M, Nollmann M
Nat Genet. 2021 Apr;53(4):477-486. doi: 10.1038/s41588-021-00816-z. Epub 2021 Apr 1. PubMed Article

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