Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.

Wettstein L, Weil T, Conzelmann C, Muller JA, Gross R, Hirschenberger M, Seidel A, Klute S, Zech F, Prelli Bozzo C, Preising N, Fois G, Lochbaum R, Knaff PM, Mailander V, Standker L, Thal DR, Schumann C, Stenger S, Kleger A, Lochnit G, Mayer B, Ruiz-Blanco YB, Hoffmann M, Sparrer KMJ, Pohlmann S, Sanchez-Garcia E, Kirchhoff F, Frick M, Munch J
Nat Commun. 2021 Mar 19;12(1):1726. doi: 10.1038/s41467-021-21972-0. PubMed Article

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