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Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching.

Shin B, Hosokawa H, Romero-Wolf M, Zhou W, Masuhara K, Tobin VR, Levanon D, Groner Y, Rothenberg EV
Proc Natl Acad Sci U S A. 2021 Jan 26;118(4). pii: 2019655118. doi: 10.1073/pnas.2019655118. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
189801E42_gRunx1_gRNA2_dTet_NGFRRetroviral delivery of guide RNA against mouse Runx1
189802E42_gRunx1_gRNA1_dTet_NGFRRetroviral delivery of guide RNA against mouse Runx1
189803E42_gRunx1_gRNA3_dTet_NGFRRetroviral delivery of guide RNA against mouse Runx1
189804E42_gRunx3_gRNA1_dTet_mTurquoise2Retroviral delivery of guide RNA against mouse Runx3
189805E42_gRunx3_gRNA2_dTet_mTurquoise2Retroviral delivery of guide RNA against mouse Runx3
189806E42_gRunx3_gRNA3_dTet_mTurquoise2Retroviral delivery of guide RNA against mouse Runx3

Antibodies from Article